John Oliver Henderson (November 13, 1909 – February 19, 1974) was a United States federal judge.
Born in Buffalo, New York, Henderson received an LL.B. from the University of Buffalo Law School in 1933. He was in the United States Army during World War II, from 1942 to 1946, achieving the rank of Lieutenant Colonel. He returned to private practice in Buffalo, and was a Clerk of the Surrogate Court of Erie County, New York from 1947 to 1948. He was the United States Attorney for the Western District of New York from 1953 to 1959.
On August 21, 1959, Henderson was nominated by President Dwight D. Eisenhower to a seat on the United States District Court for the Western District of New York vacated by Justin C. Morgan. Henderson was confirmed by the United States Senate on September 14, 1959, and received his commission on September 21, 1959. He served as chief judge from 1967 until his death on February 19, 1974.